In a study of our pregnancy rates over the past two years, we have found that the use of segmented IVF cycles have produced a 5-8% increase in pregnancy rates over the conventional IVF rates.
Segmented IVF cycles are ones where the embryo transfer is not done in the fresh stimulated IVF cycle. All of the embryos are frozen and therefore no fresh embryo transfer is performed. Cryopreserved embryos are subsequently used in a programmed frozen embryo transfer cycle.
The increased pregnancy rates in these cycles are due to several factors. First, in stimulated IVF cycles, the endometrial lining is slightly out of phase with the embryo development. Secondly, the endometrial development can be over stimulated (thicker) or under developed when compared to normal physiologic cycles. Thirdly, the ovaries in these cycles are hyperstimulated and are at an increased risk for ovarian hyperstimulation syndrome (OHSS) should a pregnancy result from the fresh transfer.
Segmented IVF is able to eliminate all of these shortcomings. Our embryo survival rate from the freeze/thaw process was over 95% in the past two years so virtually none of the embryos are lost secondary to freezing them.
This allows us to use a programmed hormone replacement cycle to create an ideal physiologic endometrial lining and precise timing for the embryo transfer. Since the ovaries are not stimulated it eliminates ovarian hyperstimulation syndrome.
The combination of these factors has resulted in a 5-8% increase in pregnancy rates over our already high IVF pregnancy rates.
Please feel free to contact us for more information about this program.