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Male fertility is largely dependent on the state of the
sperm. Sperm number, morphology and motility are important
factors. The quality of the motility of sperm, as well as
adequate sperm function is also very important for
successful fertilization. Various treatments have been
developed to deal with virtually any sperm problem. Low
sperm numbers
Oligospermia (or low sperm count) can reduce the chance
of pregnancy because it lowers the probability that an
adequate number of the sperm will reach the egg and
successfully fertilize it. The sperm count can be zero (azoospermia),
in which case there are no sperm in the ejaculate due to one
of four reasons:
- failure of the testes to produce sperm in adequate
quantities (or at all)
- failure of the sperm to mature properly
- an obstruction between the testes and the penis
preventing the sperm from being ejaculated
- retrograde ejaculation - the semen takes a wrong turn
where the vas deferens meets the urethra and ends up in
the bladder instead of being ejaculated out through the
penis
Morphology and motility
Abnormal morphology (what the sperm looks like) and poor
motility can prevent the sperm from reaching the egg. The
sperm need motility to be able to swim well and survive for
a number of hours in the female reproductive tract. If they
do meet, abnormal-looking sperm might be incapable of
fertilization. Anti sperm antibodies
Antibodies are the body’s natural defense against foreign
objects. They are part of the immune system. Men can develop
antibodies against their own sperm! This is most common in
men who have had a vasectomy reversal, genital infection or
genital trauma. The antibodies can attack the sperm by
paralyzing them, causing them to clump together or coating
them so that they can’t fertilize the egg.
Tests at Bellingham IVF
"Andrology" means for men what "gynecology" means for
women.
Bellingham IVF provides state-of-the-art diagnostic
andrology services. Our procedures comply with current World
Health Organization standards.
The following male fertility tests can be performed at
Bellingham IVF
- Semen analysis - tests the overall
appearance, acidity/alkalinity and volume of the semen,
measures the sperm concentration, motility and velocity,
and assesses morphology. However it is a very static
test and therefore has somewhat limited usefulness but
it is a good starting point.
- IVF Semen Analysis - evaluation of semen for
various assisted conception procedures. Depending on the
quality and number of sperm, different methods of
assisted conception can be recommended. This test allows
us to evaluate different sperm separation techniques to
separate the best sperm in a sample for use with various
assisted conception technologies.
- Advanced Semen Analysis - evaluation of semen
for determination of sperm function and survivability
overnight. Test is able to assist physician on type of
treatment necessary to achieve conception. This is a
dynamic sperm testing technique that was developed at
Bellingham IVF. It is based on research we published in
Fertility & Sterility in March of 1999. This test allows
us to evaluate the number of effective sperm in a sample
as well as their overnight survival. By using these
numbers we can determine the most effective treatment
method for the sperm you have.
Assisted conception treatments for Male Factor
- Assisted insemination
Men with mild to moderate sperm problems, identified
by the Advanced Semen Analysis, can benefit from
intrauterine insemination of their best sperm.
- In vitro fertilization
IVF can be effective for more sever sperm problems
because the sperm and egg can be concentrated in the
small space of a special plastic dish which can
improve the chance of fertilization.
- Sperm microinjection
This ART technique is reserved for the most severe
sperm problems. Since the development of ICSI (intra-cytoplasmic
sperm injection), fertilization can be achieved even
when there are hardly any sperm in the ejaculate or if
the sperm are poorly functioning. A single sperm is
injected directly into the body (cytoplasm) of the
egg, bypassing most of the barriers to fertilization.
- Donor insemination
For the most sever sperm problems, when direct sperm
injection is not an option for the couple for
financial or other reasons, the use of donor sperm is
an option. All donor sperm in the United States is
frozen and quarantined for 6 months before use to
prevent the transmission of most infectious diseases.
This method offers a lower cost, very effective and
safe method of dealing with severe sperm problems.
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